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HPLC is the method-of-choice for quantification of drugs in different fluids due to its sensitivity, reproducibility and specificity. Reports on the literature describe precise methods for the quantification, using HPLC, of local anesthetics in serum [11-13], urine [14] and PLGA microspheres [15]..
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2020/9/1 · This solution was then vortex mixed for 30 s and centrifuged at 14,000 × g for 15 min at room temperature. The supernatant was transferred into an Aijiren® HPLC vial, and 10 µl was injected into the HPLC-MS system to measure MTX content using the validated
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